A recent glimpse of a Red Fox whose tail was hairless except for a pompom-like tuft of fur at the very tip reminded me of the devastating effect a very small creature can have on an animal many times its size. A tiny, eyeless mite (Sarcoptes scabei) is responsible for the loss of fur associated with sarcoptic mange, the scourge of Red Foxes. After mating on a fox (often near the tail end), the male mite dies and the female burrows into the fox’s skin, laying eggs as she goes. After the eggs hatch, the larvae move to a new patch of skin, burrow in and eventually emerge as adult mites, ready to mate and continue the cycle. To add insult to injury, Red Foxes have an intense immune response to the mites’ excrement and the resulting inflammation is extremely itchy. Biting and scratching exacerbate the situation, causing new skin tears where bacteria can enter. Eventually, most foxes die of exhaustion, starvation and/or infection.